COVID 19 Tech

Omicron is trouncing the argument for “natural immunity” to COVID

A 13-year-old celebrates getting the Pfizer-BioNTech COVID-19 vaccine in Hartford, Connecticut, on May 13, 2021.

Enlarge / A 13-year-old celebrates getting the Pfizer-BioNTech COVID-19 vaccine in Hartford, Connecticut, on May 13, 2021. (credit: Getty | JOSEPH PREZIOSO )

So-called “natural immunity” against COVID-19 has always been a dodgy argument for avoiding vaccination during the pandemic. But amid omicron, natural immunity is clearly rubbish.

Unvaccinated people who have recovered from an infection with the omicron coronavirus variant are left with paltry levels of neutralizing antibodies against omicron and almost no neutralizing antibodies against any of five other coronavirus variants, including delta. People who were vaccinated before getting an omicron infection, on the other hand, have strong protection against all five variants, and they are among the highest levels of neutralizing antibodies seen against omicron.

That’s all according to a new study surveying neutralizing antibody profiles in people who have all recovered from an omicron infection, with or without pre-existing immunity. The study was published Wednesday in The New England Journal of Medicine by a team of Austrian researchers. The researchers were led by virologist Janine Kimpel of the Medical University of Innsbruck.

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